Polley J W, Figueroa A, Hung K F, Cohen M, Lakars T
Division of Plastic and Reconstructive Surgery, Cook County Hospital, Illinois, USA.
J Craniofac Surg. 1995 Mar;6(2):132-8. doi: 10.1097/00001665-199503000-00010.
Rigid microfixation has enhanced the immediate results in pediatric craniomaxillofacial surgery. The effects of rigid fixation on the development of the craniofacial skeleton, however, remain uncertain. The long-term effects of rigid microfixation on the growing craniofacial skeleton in the rabbit model were evaluated in this study. Bifrontal craniectomies were preformed in 9-day-old rabbits. The frontal bones were replaced orthotopically and fixed both anteriorly and posteriorly with either wire osteosynthesis or titanium microplates and screws. The animals were allowed to grow to craniofacial maturity, and craniofacial development was evaluated with both cephalometric and craniometric analyses. All data were statistically analyzed through analysis of variance. Regional adverse growth effects on the craniofacial skeleton with the use of both wire and rigid fixation were observed. The adverse effects were greatest with the use of rigid fixation.
坚固内固定已改善了小儿颅颌面外科手术的即时效果。然而，坚固内固定对颅面骨骼发育的影响仍不确定。本研究评估了坚固内固定对兔模型中生长的颅面骨骼的长期影响。对9日龄的兔子实施双额颅骨切除术。将额骨原位替换，并用钢丝骨固定术或微型钛板及螺钉从前部和后部进行固定。让动物生长至颅面成熟，并用头影测量和颅骨测量分析评估颅面发育情况。所有数据均通过方差分析进行统计学分析。观察到使用钢丝和坚固内固定对颅面骨骼均有局部不良生长影响。使用坚固内固定时不良影响最大。
