食管胃交界腺癌中DNA倍体的预后意义。
The prognostic significance of DNA ploidy in adenocarcinomas of the esophagogastric junction.
作者信息
Sarbia M, Molsberger G, Willers R, Horstmann O, Schroders C, Porschen R, Gabbert H E
机构信息
Department of Pathology, Heinrich-Heine University, Düsseldorf, Germany.
出版信息
J Cancer Res Clin Oncol. 1996;122(3):186-88. doi: 10.1007/BF01366961.
Abstract
DNA aneuploidy, as determined by flow cytometry, was detected in 36 out of 59 adenocarcinomas of the esophagogastric junction (61.0%). DNA aneuploidy was more frequent in tumors with infiltrative growth pattern and in high pT categories. No correlation was found with pN category, grading and Laurén's classification. In contrast to clinicopathological parameters, DNA ploidy has no impact on patients survival in univariate survival analysis.
摘要
通过流式细胞术测定，在59例食管胃交界腺癌中有36例检测到DNA非整倍体（61.0%）。DNA非整倍体在具有浸润性生长模式的肿瘤和高pT类别中更为常见。未发现与pN类别、分级和劳伦分类相关。与临床病理参数相反，在单因素生存分析中，DNA倍性对患者生存无影响。
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