Ellis F H, Gibb S P, Watkins E
Department of Thoracic and Cardiovascular Surgery, Lahey Clinic Medical Center, Burlington, MA 01805.
Ann Surg. 1988 Sep;208(3):354-61. doi: 10.1097/00000658-198809000-00013.
Between 1970 and 1988, 149 patients with carcinoma of the cardia were operated on at the Lahey Clinic. Of these patients, 127 (85%) underwent resection; 23 (18.1%) were of a palliative nature. More than 75% had Stage III and IV disease. One patient (0.8%) died within 30 days of the operation of a myocardial infarct. Two other patients failed to leave the hospital. Of 25 postoperative complications, 14 (11%) were considered major. Palliation of dysphagia was successful in 80% of patients. The actuarial 5-year survival rate was 22.4%. Of patients with Stage I and II disease, 36.6% survived for 5 years, and of patients with Stage III disease, 22.5% survived. No patient with Stage IV disease lived for longer than 1 year. It is concluded that limited esophagogastrectomy can be performed in most patients with carcinoma of the cardia with low mortality and morbidity and with satisfactory long-term survival.
1970年至1988年间,149例贲门癌患者在拉希诊所接受了手术治疗。其中,127例(85%)接受了切除术;23例(18.1%)为姑息性手术。超过75%的患者患有III期和IV期疾病。1例患者(0.8%)在术后30天内因心肌梗死死亡。另外2例患者未能出院。在25例术后并发症中,14例(11%)被认为是严重并发症。80%的患者吞咽困难缓解成功。精算5年生存率为22.4%。I期和II期疾病患者中,36.6%存活了5年;III期疾病患者中,22.5%存活。没有IV期疾病患者存活超过1年。结论是,大多数贲门癌患者可以进行有限的食管胃切除术,死亡率和发病率低,长期生存率令人满意。