Kassan D G, Lynch A M, Stiller M J
Department of Dermatology, Harvard Medical School, Massachusetts General Hospital, Boston, USA.
J Am Acad Dermatol. 1996 Apr;34(4):657-66. doi: 10.1016/s0190-9622(96)80069-7.
Iontophoresis and phonophoresis are emerging technologies capable of enhancing drug penetration through the stratum corneum, the principal barrier to percutaneous absorption. With utilization of applied electric current or ultrasonic waves, respectively, iontophoresis and phonophoresis have shown efficacy in an increasing number of clinical applications. This article reviews the underlying principles, current status, and potential of iontophoresis and phonophoresis in dermatologic therapy.
离子导入法和超声透入法是能够增强药物透过角质层（经皮吸收的主要屏障）的新兴技术。离子导入法和超声透入法分别利用施加的电流或超声波，已在越来越多的临床应用中显示出疗效。本文综述了离子导入法和超声透入法在皮肤科治疗中的基本原理、现状及潜力。
