1例从骨髓增生异常综合征进展为急性髓系白血病（M2型）患者中的c-MYC扩增 - Suppr

Suppr

超能文献

c-MYC amplification in a case of progression from MDS to AML (M2).

作者信息

de Souza Fernandez T, Silva M L, De Souza J, De Paula M T, Abdelhay E

出版信息

Cancer Genet Cytogenet. 1996 Feb;86(2):183-4. doi: 10.1016/0165-4608(95)00191-3.

DOI:10.1016/0165-4608(95)00191-3

PMID:8603353

Abstract

摘要

相似文献

c-MYC amplification in a case of progression from MDS to AML (M2).1例从骨髓增生异常综合征进展为急性髓系白血病（M2型）患者中的c-MYC扩增

Cancer Genet Cytogenet. 1996 Feb;86(2):183-4. doi: 10.1016/0165-4608(95)00191-3.

IS THE AMPLIFICATION OF c-MYC, MLL AND RUNX1 GENES IN AML AND MDS PATIENTS WITH TRISOMY 8, 11 AND 21 A FACTOR FOR A CLONAL EVOLUTION IN THEIR KARYOTYPE?8号、11号和21号染色体三体的急性髓系白血病和骨髓增生异常综合征患者中c-MYC、MLL和RUNX1基因的扩增是否是其核型克隆进化的一个因素？

Tsitol Genet. 2015 May-Jun;49(3):25-32.

Double minute chromosomes in a patient with myelodysplastic syndrome transforming into acute myeloid leukemia.一名骨髓增生异常综合征转化为急性髓系白血病患者的双微体染色体

Cancer Genet Cytogenet. 1999 Feb;109(1):76-8. doi: 10.1016/s0165-4608(98)00133-2.

Clonal selection of 11q CN-LOH and CBL gene mutation in a serially studied patient during MDS progression to AML.在 MDS 进展为 AML 的患者中进行的连续研究中，11q CN-LOH 和 CBL 基因突变的克隆选择。

Leuk Res. 2010 Nov;34(11):1539-42. doi: 10.1016/j.leukres.2010.07.004. Epub 2010 Aug 1.

Acute myeloid leukemia with MYC rearrangement and JAK2 V617F mutation.伴有MYC重排和JAK2 V617F突变的急性髓系白血病

Cancer Genet. 2015 Nov;208(11):571-4. doi: 10.1016/j.cancergen.2015.06.004. Epub 2015 Jun 25.

Double minute chromosomes in acute myeloid leukemia, myelodysplastic syndromes, and chronic myelomonocytic leukemia are associated with micronuclei, MYC or MLL amplification, and complex karyotype.急性髓系白血病、骨髓增生异常综合征和慢性粒单核细胞白血病中的双微体染色体与微核、MYC或MLL扩增以及复杂核型相关。

Cancer Genet. 2016 Jul-Aug;209(7-8):313-20. doi: 10.1016/j.cancergen.2016.05.072. Epub 2016 May 27.

MDS and AML with trisomy 8 as the sole chromosome aberration show different sex ratios and prognostic profiles: a study of 115 published cases.以8号染色体三体作为唯一染色体畸变的骨髓增生异常综合征和急性髓系白血病表现出不同的性别比例和预后特征：对115例已发表病例的研究

Am J Hematol. 1997 Dec;56(4):224-9. doi: 10.1002/(sici)1096-8652(199712)56:4<224::aid-ajh5>3.0.co;2-z.

Detectable FLT3-ITD or RAS mutation at the time of transformation from MDS to AML predicts for very poor outcomes.从骨髓增生异常综合征（MDS）转化为急性髓系白血病（AML）时可检测到的FLT3内部串联重复（FLT3-ITD）或RAS突变预示预后极差。

Leuk Res. 2015 Dec;39(12):1367-74. doi: 10.1016/j.leukres.2015.10.005. Epub 2015 Oct 19.

Co-existence of pseudo-Chediak-Higashi anomaly and double minutes containing C-MYC oncogene in three patients with AML M2.三名急性髓系白血病M2型患者中假性齐-希畸形与含有C-MYC癌基因的双微体并存。

Leukemia. 2002 Jan;16(1):152-4. doi: 10.1038/sj.leu.2402323.

Trisomy 4 associated with double minute chromosomes and MYC amplification in acute myeloblastic leukemia.急性髓细胞白血病中与双微体染色体及MYC扩增相关的4号染色体三体。

Ann Genet. 2004 Oct-Dec;47(4):423-7. doi: 10.1016/j.anngen.2004.08.004.

引用本文的文献

Aberrant Expression of in Pediatric Patients with Myelodysplastic Syndrome: A Potential Biomarker of Leukemic Evolution.在儿童骨髓增生异常综合征患者中表达异常：白血病演变的潜在生物标志物。

Biomed Res Int. 2019 Dec 10;2019:3176565. doi: 10.1155/2019/3176565. eCollection 2019.

Cytogenetic as an important tool for diagnosis and prognosis for patients with hypocellular primary myelodysplastic syndrome.细胞遗传学作为低细胞性原发性骨髓增生异常综合征患者诊断和预后评估的重要工具。

Biomed Res Int. 2014;2014:542395. doi: 10.1155/2014/542395. Epub 2014 Aug 11.

Over-expression of cancerous inhibitor of PP2A (CIP2A) in bone marrow cells from patients with a group of high-risk myelodysplastic syndromes.一组高危骨髓增生异常综合征患者骨髓细胞中蛋白磷酸酶2A癌性抑制剂（CIP2A）的过表达。

Pathol Oncol Res. 2014 Apr;20(2):399-407. doi: 10.1007/s12253-013-9709-y. Epub 2013 Oct 26.

A pilot study of high-throughput, sequence-based mutational profiling of primary human acute myeloid leukemia cell genomes.一项关于原代人类急性髓系白血病细胞基因组的高通量、基于序列的突变分析的初步研究。

Proc Natl Acad Sci U S A. 2003 Nov 25;100(24):14275-80. doi: 10.1073/pnas.2335924100. Epub 2003 Nov 12.

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验