Zorbas Y G, Ivanov A L, Federenko Y F
Hypokinetic Physiology Laboratory, Athens, Greece.
Rev Esp Fisiol. 1995 Sep;51(3):155-62.
Sodium and potassium concentrations in organs and tissues of rats have been determined during hypokinesia (HK) and posthypokinesia (post-HK) periods. The study was performed on 180 male Wistar rats with an initial body weight of 370 to 390 g. They were divided into control and experimental groups: the 1st group of rats was placed under ordinary vivarium conditions (control) and the 2nd group was subjected to 90 days of HK (hypokinetic animals). The animals were kept in small individual wooden cages which restricted their movements in all directions without hindering feed and water intake. On the 30th, 60th and 90th day of the HK period and on the 5th, 10th and 15th day of the post-HK period animals were decapitated, and potassium and sodium concentrations were measured in the myocardium, skeletal muscles, erythrocytes and plasma. Fluid content was also determined in the myocardium and skeletal muscles. During both the HK period and initial stages of the post-HK period the concentration of sodium and potassium in the myocardium, skeletal muscle, plasma and erythrocytes as well as water content in the myocardium and skeletal muscle changed significantly.
在运动减少期（HK）和运动减少后期（post-HK），对大鼠器官和组织中的钠和钾浓度进行了测定。该研究以180只初始体重为370至390克的雄性Wistar大鼠为对象。它们被分为对照组和实验组：第1组大鼠置于普通饲养条件下（对照组），第2组大鼠经历90天的运动减少期（运动减少动物）。动物被饲养在小型个体木制笼中，限制它们各个方向的活动，但不妨碍进食和饮水。在运动减少期的第30、60和90天以及运动减少后期的第5、10和15天，将动物断头，并测定心肌、骨骼肌、红细胞和血浆中的钾和钠浓度。还测定了心肌和骨骼肌中的液体含量。在运动减少期和运动减少后期的初始阶段，心肌、骨骼肌、血浆和红细胞中的钠和钾浓度以及心肌和骨骼肌中的含水量均发生了显著变化。
