Castellani G
Arch Sci Med (Torino). 1977 Jan-Mar;134(1):73-80.
Ampicillin at 2-4 g/day per os and 2 g/12 hr slow venous drip gave good results in 88% of 25 and 90% of 20 cases of bronchopneumopathy respectively. Tolerance was excellent in all but 4 cases. In spite of the introduction of new semi-synthetic penicillins, it is felt that ampicillin must still be rated as one of the most effective and best tolerated antibiotics. At the doses at present recommended, it is of particular significance in the treatment of aged subjects.
氨苄西林每日口服2 - 4克以及每12小时缓慢静脉滴注2克,分别使25例支气管肺炎患者中的88%和20例患者中的90%取得了良好疗效。除4例患者外,耐受性均极佳。尽管已引入新的半合成青霉素,但人们认为氨苄西林仍必须被视为最有效且耐受性最佳的抗生素之一。在目前推荐的剂量下,它在老年患者的治疗中具有特别重要的意义。