Martin R J
University of Colorado Health Sciences Center, Denver, USA.
Hosp Pract (1995). 1996 Apr 15;31(4):61-4, 69-74, 79-80.
Patients first should be evaluated for a mimicking or coexisting condition, such as vocal cord dysfunction or endobronchial stenosis. Once the diagnosis is clearly established and any triggering factors have been addressed, chronotherapy is the key to management--that is, timing drug delivery so that serum levels peak when disease manifestations are at their worst, often in the middle of the night.
首先应评估患者是否存在类似情况或并存疾病,如声带功能障碍或支气管内狭窄。一旦明确诊断并解决了任何触发因素,时间疗法是治疗的关键,即调整给药时间,使血清水平在疾病表现最严重时达到峰值,通常是在午夜时分。