Lee C, Mok M S, Barnes A, Katz R L
Br J Anaesth. 1977 May;49(5):485-9. doi: 10.1093/bja/49.5.485.
The possibility of "recurarization" after antagonism of the competitive neuromuscular block with anticholinesterases was studied. Observations were made on the time-course of the block in five patients at risk from recurarization because of multiple organ failure and who demonstrated unusually prolonged blockade. In none of these patients did the block recur. We conclude that, provided spontaneous recovery of neuromuscular transmission has made progress before the antagonism, and that the patient does not deteriorate or become exhausted afterwards, recurarization is unlikely.
研究了用抗胆碱酯酶药拮抗竞争性神经肌肉阻滞作用后出现“再箭毒化”的可能性。对5例因多器官功能衰竭有再箭毒化风险且神经肌肉阻滞时间异常延长的患者的阻滞时间进程进行了观察。这些患者均未出现阻滞复发。我们得出结论，只要在拮抗作用前神经肌肉传递已开始自发恢复，且患者此后病情不恶化或不出现衰竭，就不太可能发生再箭毒化。
