Hara K, Sonenberg M
Biochim Biophys Acta. 1977 May 27;492(1):95-101. doi: 10.1016/0005-2795(77)90217-3.
Polyalanylation of bovine somatotropin peptide 96-133 has been investigated. Polyalanylated peptides contained an average of 3-50 additional alanines per mole of peptide. As indicated by circular dichroism, the parent peptide and the polyalanylated peptides were helical at pH 4.0. The biological activity per mole of peptide with 50 additional alanies was approximately the same as that of the parent peptide.
已对牛生长激素肽96 - 133的聚丙氨酸化进行了研究。聚丙氨酸化肽每摩尔肽平均含有3 - 50个额外的丙氨酸。如圆二色性所示，亲本肽和聚丙氨酸化肽在pH 4.0时呈螺旋状。每摩尔含有50个额外丙氨酸的肽的生物活性与亲本肽大致相同。
