蛋白质缺乏大鼠后代肠道的出生后早期发育
Early postnatal development of the intestine in progeny of protein-deprived rats.
作者信息
Shrader R E, Ferlatte M I, Zeman F J
出版信息
Biol Neonate. 1977;31(3-4):181-98. doi: 10.1159/000240959.
PMID:861317
Abstract
Development of the small intestine was studied in newborn, and 4-, 8-, and 12-day-old young of rats fed diets, during gestation, containing 24 or 4% casein as the source of protein. Newborn prenatally protein-deprived rats had shorter, narrower intestines, reduced numbers of villi per unit length, shorter villi, and reduced numbers of absorptive cells and crypt cells. These differences had disappeared by the age of 12 days in adequately fed pups that had survived to that age.
摘要
研究了新生大鼠以及出生后4天、8天和12天的幼鼠小肠的发育情况，这些幼鼠的母亲在妊娠期食用含有24%或4%酪蛋白作为蛋白质来源的日粮。产前蛋白质缺乏的新生大鼠的小肠更短、更窄，单位长度内绒毛数量减少，绒毛更短，吸收细胞和隐窝细胞数量减少。在存活到12日龄且喂养充足的幼崽中，这些差异到12日龄时已消失。
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