重新审视纤连蛋白结合在金黄色葡萄球菌引起的心内膜炎中的作用。
Reconsideration of the role of fibronectin binding in endocarditis caused by Staphylococcus aureus.
作者信息
Flock J I, Hienz S A, Heimdahl A, Schennings T
机构信息
Department of Microbiology, Immunology, Pathology, and Infectious Diseases, Karolinska Institutet, Huddinge University Hospital, Sweden.
出版信息
Infect Immun. 1996 May;64(5):1876-8. doi: 10.1128/iai.64.5.1876-1878.1996.
Abstract
The adherence characteristics in vivo and virulence of two isogenic strains of Staphylococcus aureus differing in fibronectin binding were compared in a rat model of catheter-induced infective endocarditis. No differences were found between the two strains. The results strongly point to the multifactorial nature of bacterial adherence to damaged heart valves and suggest that other binding functions can compensate for the lack of fibronectin binding in S. aureus.
摘要
在导管诱导的感染性心内膜炎大鼠模型中，比较了两株纤维连接蛋白结合能力不同的同源金黄色葡萄球菌菌株在体内的黏附特性和毒力。两株菌株之间未发现差异。结果有力地表明细菌黏附于受损心脏瓣膜具有多因素性质，并提示其他结合功能可弥补金黄色葡萄球菌中纤维连接蛋白结合的缺乏。
相似文献
1
Reconsideration of the role of fibronectin binding in endocarditis caused by Staphylococcus aureus.重新审视纤连蛋白结合在金黄色葡萄球菌引起的心内膜炎中的作用。
Infect Immun. 1996 May;64(5):1876-8. doi: 10.1128/iai.64.5.1876-1878.1996.
2
Staphylococcus aureus endocarditis: distinct mechanisms of bacterial adhesion to damaged and inflamed heart valves.金黄色葡萄球菌心内膜炎：细菌黏附于受损和炎症心脏瓣膜的不同机制。
Eur Heart J. 2019 Oct 14;40(39):3248-3259. doi: 10.1093/eurheartj/ehz175.
3
Impacts of sarA and agr in Staphylococcus aureus strain Newman on fibronectin-binding protein A gene expression and fibronectin adherence capacity in vitro and in experimental infective endocarditis.金黄色葡萄球菌纽曼菌株中sarA和agr对纤连蛋白结合蛋白A基因表达及体外和实验性感染性心内膜炎中纤连蛋白黏附能力的影响
Infect Immun. 2004 Mar;72(3):1832-6. doi: 10.1128/IAI.72.3.1832-1836.2004.
4
Natural variability of in vitro adherence to fibrinogen and fibronectin does not correlate with in vivo infectivity of Staphylococcus aureus.体外黏附纤维蛋白原和纤维连接蛋白的自然变异与金黄色葡萄球菌的体内感染性无关。
Infect Immun. 2010 Apr;78(4):1711-6. doi: 10.1128/IAI.01274-09. Epub 2010 Jan 11.
5
Immunization with fibronectin binding protein from Staphylococcus aureus protects against experimental endocarditis in rats.用金黄色葡萄球菌纤连蛋白结合蛋白进行免疫可预防大鼠实验性心内膜炎。
Microb Pathog. 1993 Sep;15(3):227-36. doi: 10.1006/mpat.1993.1073.
6
Fibrinogen and fibronectin binding cooperate for valve infection and invasion in Staphylococcus aureus experimental endocarditis.在金黄色葡萄球菌实验性心内膜炎中，纤维蛋白原和纤连蛋白结合共同作用于瓣膜感染和侵袭。
J Exp Med. 2005 May 16;201(10):1627-35. doi: 10.1084/jem.20050125.
7
Reduced adherence to traumatized rat heart valves by a low-fibronectin-binding mutant of Staphylococcus aureus.金黄色葡萄球菌的低纤连蛋白结合突变体对创伤大鼠心脏瓣膜的黏附性降低。
Infect Immun. 1989 Aug;57(8):2306-12. doi: 10.1128/iai.57.8.2306-2312.1989.
8
Development of a mouse model of induced Staphylococcus aureus infective endocarditis.诱导性金黄色葡萄球菌感染性心内膜炎小鼠模型的建立
Comp Med. 2007 Dec;57(6):563-9.
9
Adhesion of Staphylococcus aureus to collagen is not a major virulence determinant for septic arthritis, osteomyelitis, or endocarditis.金黄色葡萄球菌与胶原蛋白的黏附并非脓毒性关节炎、骨髓炎或心内膜炎的主要毒力决定因素。
J Infect Dis. 1999 Jan;179(1):291-3. doi: 10.1086/314576.
10
Collagen binding of Staphylococcus aureus is a virulence factor in experimental endocarditis.金黄色葡萄球菌的胶原结合是实验性心内膜炎中的一种毒力因子。
J Infect Dis. 1996 Jul;174(1):83-8. doi: 10.1093/infdis/174.1.83.
引用本文的文献
1
The Application of Rat Models in Infections.大鼠模型在感染中的应用。
Pathogens. 2024 May 21;13(6):434. doi: 10.3390/pathogens13060434.
2
Treponema pallidum subsp. pallidum TP0136 protein is heterogeneous among isolates and binds cellular and plasma fibronectin via its NH2-terminal end.梅毒螺旋体苍白亚种TP0136蛋白在分离株中具有异质性，并通过其氨基末端结合细胞和血浆纤连蛋白。
PLoS Negl Trop Dis. 2015 Mar 20;9(3):e0003662. doi: 10.1371/journal.pntd.0003662. eCollection 2015 Mar.
3
Natural variability of in vitro adherence to fibrinogen and fibronectin does not correlate with in vivo infectivity of Staphylococcus aureus.体外黏附纤维蛋白原和纤维连接蛋白的自然变异与金黄色葡萄球菌的体内感染性无关。
Infect Immun. 2010 Apr;78(4):1711-6. doi: 10.1128/IAI.01274-09. Epub 2010 Jan 11.
4
Inactivation of a two-component signal transduction system, SaeRS, eliminates adherence and attenuates virulence of Staphylococcus aureus.双组分信号转导系统SaeRS的失活消除了金黄色葡萄球菌的黏附并减弱了其毒力。
Infect Immun. 2006 Aug;74(8):4655-65. doi: 10.1128/IAI.00322-06.
5
Bartonella henselae Pap31, an extracellular matrix adhesin, binds the fibronectin repeat III13 module.汉赛巴尔通体Pap31是一种细胞外基质黏附素，可结合纤连蛋白重复III13模块。
Infect Immun. 2006 May;74(5):2513-21. doi: 10.1128/IAI.74.5.2513-2521.2006.
6
Truncation of fibronectin-binding proteins in Staphylococcus aureus strain Newman leads to deficient adherence and host cell invasion due to loss of the cell wall anchor function.金黄色葡萄球菌纽曼菌株中纤连蛋白结合蛋白的截短会导致细胞壁锚定功能丧失，从而导致黏附及宿主细胞侵袭能力不足。
Infect Immun. 2004 Dec;72(12):7155-63. doi: 10.1128/IAI.72.12.7155-7163.2004.
7
The fibronectin-binding proteins of Staphylococcus aureus may promote mammary gland colonization in a lactating mouse model of mastitis.金黄色葡萄球菌的纤连蛋白结合蛋白可能会在乳腺炎的泌乳小鼠模型中促进乳腺定植。
Infect Immun. 2003 Apr;71(4):2292-5. doi: 10.1128/IAI.71.4.2292-2295.2003.
8
Analysis of Ebh, a 1.1-megadalton cell wall-associated fibronectin-binding protein of Staphylococcus aureus.金黄色葡萄球菌1.1兆道尔顿细胞壁相关纤连蛋白结合蛋白Ebh的分析。
Infect Immun. 2002 Dec;70(12):6680-7. doi: 10.1128/IAI.70.12.6680-6687.2002.
9
Increased virulence of a fibronectin-binding protein mutant of Staphylococcus aureus in a rat model of pneumonia.金黄色葡萄球菌纤连蛋白结合蛋白突变体在大鼠肺炎模型中的毒力增强
Infect Immun. 2002 Jul;70(7):3865-73. doi: 10.1128/IAI.70.7.3865-3873.2002.
10
Insertional inactivation of Eap in Staphylococcus aureus strain Newman confers reduced staphylococcal binding to fibroblasts.金黄色葡萄球菌纽曼菌株中Eap的插入失活导致葡萄球菌与成纤维细胞的结合减少。
Infect Immun. 2002 Jun;70(6):2933-40. doi: 10.1128/IAI.70.6.2933-2940.2002.
本文引用的文献
1
Adhesion properties of mutants of Staphylococcus aureus defective in fibronectin-binding proteins and studies on the expression of fnb genes.金黄色葡萄球菌纤连蛋白结合蛋白缺陷型突变体的黏附特性及fnb基因表达研究
Mol Microbiol. 1995 Sep;17(6):1143-52. doi: 10.1111/j.1365-2958.1995.mmi_17061143.x.
2
Immunization with fibronectin binding protein from Staphylococcus aureus protects against experimental endocarditis in rats.用金黄色葡萄球菌纤连蛋白结合蛋白进行免疫可预防大鼠实验性心内膜炎。
Microb Pathog. 1993 Sep;15(3):227-36. doi: 10.1006/mpat.1993.1073.
3
Identification and biochemical characterization of the ligand binding domain of the collagen adhesin from Staphylococcus aureus.金黄色葡萄球菌胶原蛋白黏附素配体结合结构域的鉴定与生化特性分析
Biochemistry. 1993 Oct 26;32(42):11428-35. doi: 10.1021/bi00093a021.
4
Use of adhesion-defective mutants of Staphylococcus aureus to define the role of specific plasma proteins in promoting bacterial adhesion to canine arteriovenous shunts.利用金黄色葡萄球菌的黏附缺陷突变体来确定特定血浆蛋白在促进细菌黏附于犬动静脉分流管中的作用。
Infect Immun. 1995 Feb;63(2):585-90. doi: 10.1128/iai.63.2.585-590.1995.
5
Role of Staphylococcus aureus coagulase and clumping factor in pathogenesis of experimental endocarditis.金黄色葡萄球菌凝固酶和聚集因子在实验性心内膜炎发病机制中的作用。
Infect Immun. 1995 Dec;63(12):4738-43. doi: 10.1128/iai.63.12.4738-4743.1995.
6
Evidence that the heparin-binding consensus sequence of vitronectin is recognized by Staphylococcus aureus.有证据表明金黄色葡萄球菌可识别玻连蛋白的肝素结合共有序列。
J Biochem. 1994 Aug;116(2):457-63. doi: 10.1093/oxfordjournals.jbchem.a124546.
7
Platelet interaction with the extracellular matrix produced by cultured endothelial cells: a model to study the thrombogenicity of isolated subendothelial basal lamina.血小板与培养的内皮细胞产生的细胞外基质的相互作用：一种研究分离的内皮下基膜血栓形成性的模型。
Thromb Res. 1982 Oct 15;28(2):179-91. doi: 10.1016/0049-3848(82)90260-2.
8
Natural history of aortic valve endocarditis in rats.大鼠主动脉瓣心内膜炎的自然病史。
Infect Immun. 1982 Jul;37(1):127-31. doi: 10.1128/iai.37.1.127-131.1982.
9
Experimental bacterial endocarditis. I. Colonization of a sterile vegetation.实验性细菌性心内膜炎。I. 无菌赘生物的定植
Br J Exp Pathol. 1972 Feb;53(1):44-9.
10
Extracellular matrix proteins (fibronectin, laminin, and type IV collagen) bind and aggregate bacteria.细胞外基质蛋白（纤连蛋白、层粘连蛋白和IV型胶原蛋白）结合并聚集细菌。
Am J Pathol. 1985 Jul;120(1):13-21.
Zotero 插件