Pons A, Armand J P, Voigt J J, Combes P F
Bull Cancer. 1977;64(1):79-92.
The authors present a critical review of 14 cases of malignant thymomas. They point out that the development of the tumours is similar to Hodgkin disease's (13 relapses in contiguous areas), that surgery is never sufficient for cure and that radiosensitivity is high (in 8 patients radiotherapy alone results in a total and early regression of the tumour). Therefore the authors propose a complementary post-operative treatment by limited irradiation and MOPP type polychemotherapy. This temporary choice of treatment can be reevaluated after further case studies. To facilitate this they wish that a cooperative project could gather the rare and dispersed observations of different centers.
作者对14例恶性胸腺瘤进行了批判性回顾。他们指出，肿瘤的发展与霍奇金病相似（13例在相邻区域复发），手术永远不足以治愈，且放射敏感性高（8例患者仅放疗就能使肿瘤完全早期消退）。因此，作者建议通过有限照射和MOPP型多药化疗进行术后辅助治疗。这种临时的治疗选择可在进一步的病例研究后重新评估。为便于此，他们希望有一个合作项目能够收集不同中心罕见且分散的观察结果。
