Demetriades D, Theodorou D, Murray J, Asensio J A, Cornwell E E, Velmahos G, Belzberg H, Berne T V
Division of Trauma, Los Angeles County and University of Southern California Medical Center 90033, USA.
J Trauma. 1996 May;40(5):761-3. doi: 10.1097/00005373-199605000-00013.
This study was designed to investigate the epidemiology and prognostic factors determining survival in penetrating injuries of the aorta.
This was a retrospective analysis of all patients with penetrating aortic injuries, admitted to a large, level I trauma center. The following factors were analyzed for their role in determining survival: mechanism of injury, anatomical site of the aortic injury, initial blood pressure on admission, need for emergency room thoracotomy, and the introduction of a dedicated trauma program with an attending surgeon in-house.
There were 93 patients with penetrating aortic injuries over a 5-year period. The abdominal aorta was injured in 67 patients (72%) and the thoracic aorta in 26 (28%). Most of the victims (82.5%) were admitted in shock and 41% had an unrecordable blood pressure on admission. Victims with injury to the thoracic aorta were more likely to have an unrecordable blood pressure on admission than patients with abdominal aortic injuries (73% vs 28.4%), and more likely to require an emergency room thoracotomy (76.9% vs 20.9%). Thirty-four patients (36.6%) required an emergency room thoracotomy and there were no survivors. The overall mortality was 80.6% (87.5% for gunshot injuries, 64.7 % for knife injuries). Patients with abdominal aortic injuries were three times more likely to survive than those with thoracic aortic injuries (23.9% vs 7.7%). The introduction of a dedicated trauma program, which resulted in significant reduction of mortality in other types of severe trauma, had no effect on the outcome in aortic injuries.
Penetrating aortic injuries still have a very high mortality rate with no improvement in survival despite improved trauma services. Injury to the thoracic aorta, gunshot wounds, unrecordable blood pressure on admission, and the need for emergency room thoracotomy, are important predictors of high mortality.
本研究旨在调查主动脉穿透伤的流行病学及决定生存的预后因素。
这是一项对一所大型一级创伤中心收治的所有主动脉穿透伤患者的回顾性分析。分析了以下因素在决定生存方面的作用:损伤机制、主动脉损伤的解剖部位、入院时的初始血压、是否需要急诊室开胸手术,以及引入由主治外科医生在院的专门创伤治疗方案。
在5年期间有93例主动脉穿透伤患者。67例(72%)患者腹主动脉受伤,26例(28%)患者胸主动脉受伤。大多数受害者(82.5%)入院时处于休克状态,41%患者入院时血压无法记录。胸主动脉损伤的受害者入院时血压无法记录的可能性高于腹主动脉损伤患者(73%对28.4%),且更有可能需要急诊室开胸手术(76.9%对20.9%)。34例患者(36.6%)需要急诊室开胸手术,无一例存活。总体死亡率为80.6%(枪伤为87.5%,刀伤为64.7%)。腹主动脉损伤患者的存活可能性是胸主动脉损伤患者的三倍(23.9%对7.7%)。引入专门的创伤治疗方案虽在其他类型严重创伤中显著降低了死亡率,但对主动脉损伤的结局并无影响。
尽管创伤服务有所改善,但主动脉穿透伤的死亡率仍然很高,生存率没有提高。胸主动脉损伤、枪伤、入院时血压无法记录以及需要急诊室开胸手术是高死亡率的重要预测因素。