Stokkel M P, Boot C N, van Eck-Smit B L
Department of Diagnostic Radiology and Nuclear Medicine, University Hospital Leiden, The Netherlands.
Laryngoscope. 1996 Mar;106(3 Pt 1):338-40. doi: 10.1097/00005537-199603000-00018.
Malignant external otitis (MEO) is a recognized entity characterized by a stubborn Pseudomonas external otitis; it has been most frequently observed in elderly diabetic patients. Early diagnosis is necessary for successful treatment but, despite a widespread inflammatory response, routine plain x-ray studies and computed tomography (CT) scanning show no abnormalities in its early stage. In this report, the clinical value of gallium 67 (Ga 67) single photon emission CT (SPECT) is studied in three patients suspected of having MEO, and the results are compared with findings on CT scan and laboratory tests. These results confirm that the high sensitivity of GA 67 SPECT in the initial recognition of MEO provides a more adequate technique than CT scan. Furthermore, Ga 67 scintigraphy appears to be highly accurate for follow-up evaluation of these patients.
恶性外耳道炎（MEO）是一种公认的疾病，其特征为顽固性外耳道假单胞菌感染；多见于老年糖尿病患者。早期诊断对成功治疗至关重要，但尽管有广泛的炎症反应，常规的普通X线检查和计算机断层扫描（CT）在其早期阶段均未显示异常。在本报告中，对3例疑似MEO的患者研究了镓67（Ga 67）单光子发射计算机断层扫描（SPECT）的临床价值，并将结果与CT扫描及实验室检查结果进行了比较。这些结果证实，Ga 67 SPECT在MEO初始诊断中的高敏感性提供了一种比CT扫描更合适的技术。此外，Ga 67闪烁扫描术在对这些患者的随访评估中似乎具有高度准确性。
