Korzeniewska-Koseła M, Meleniewska-Maciszewska A, Zagdańska J, Krakówka P
I Kliniki Gruźlicy i Chorób Płuc Instytutu Gruźlicy i Chorób Płuc, Warszawie.
Pneumonol Pol. 1990 Nov-Dec;58(11-12):620-3.
The course of allergic alveolitis was observed in 19 patients. The diagnosis was based on medical history, exposition to organic dust, clinical findings, respiratory function and in selected cases on results of transbronchial lung biopsy. All patients presented restrictive patterns of lung function abnormalities. Although a clinical improvement was seen, in none of the patients was a normalization of respiratory function observed. The results of treatment were more promising in patients with a shorter time between the onset of symptoms and making of diagnosis. Isolation from allergens resulted in better effect without prophylactic treatment with prednisone. Steroid therapy did not effect the relapses nor worsening of the respiratory function.
对19例过敏性肺泡炎患者的病程进行了观察。诊断依据病史、接触有机粉尘情况、临床症状、呼吸功能,部分病例还依据经支气管肺活检结果。所有患者均呈现肺功能异常的限制性模式。尽管临床症状有所改善,但未观察到任何患者的呼吸功能恢复正常。症状出现至确诊时间较短的患者,治疗效果更有前景。脱离过敏原在未使用泼尼松预防性治疗的情况下效果更佳。类固醇治疗对呼吸功能的复发及恶化并无影响。