Tarkó M
Morphol Igazsagugyi Orv Sz. 1979 Jan;19(1):38-47.
A staining method suitable for the selective demonstration of X-chromation and other types of chromatins is described. On the basis of the behaviour of chromations four types of cells (in males only two) can be distinguished. From the changes of the proportion various types of cells, conclusions can be drawn concerning the alteratins of cell kinetics. These changes raise the question of the existence of a general basical biological rhythm. The duration of a cycle in this rhythm is 73 days. These cycles considerably modify the course of different diseases and the efficacy of the therapy applied. Thus the investigation of the chromatin is a useful tool for the prognosis and the therapy. The chronic myeloid leukaemia was detaily analyzed. Practical importance of the data obtained seems to be obvious.
描述了一种适用于选择性显示X染色质和其他类型染色质的染色方法。根据染色质的行为，可以区分出四种类型的细胞（仅男性有两种）。根据各类细胞比例的变化，可以得出关于细胞动力学改变的结论。这些变化引发了关于普遍基本生物节律存在的问题。这种节律一个周期的时长为73天。这些周期极大地改变了不同疾病的病程以及所应用治疗的疗效。因此，对染色质的研究是用于预后和治疗的有用工具。对慢性粒细胞白血病进行了详细分析。所获数据的实际重要性似乎是显而易见的。
