Birkett A, Muir J, Phillips J, Jones G, O'Dea K
School of Nutrition and Public Health, Deakin University, Malvern, Australia.
Am J Clin Nutr. 1996 May;63(5):766-72. doi: 10.1093/ajcn/63.5.766.
We investigated the effect of resistant starch (RS) on markers of colonic protein metabolism. Eleven subjects participated in a randomized crossover study in which they consumed either high-RS (39 +/- 3 g/d, -chi +/- SEM) or low-RS (5 +/- 0.4 g/d) diets for 3 wk. All other macronutrients were kept constant. During the high-RS diet daily excretion of fecal nitrogen increased from 1.84 +/- 0.15 to 2.86 +/- 0.42 g/d (P < 0.01) and excretion of fecal phenols fell from 9.2 +/- 1.4 to 5.3 +/- 0.8 mg/d (P < 0.01). Fecal concentrations of ammonia decreased from 397 +/- 33 to 278 +/- 49 microgram/g (P < 0.01) and phenols decreased from 69 +/- 8 to 39 +/- 10 microgram/g (P < 0.001). Daily output of urinary ammonia, urea, phenols, and total nitrogen did not change significantly, but pH decreased from 6.4 +/- 0.1 to 6.2 +/- 0.1 (P < 0.05) during the high-RS period. These results suggest that RS significantly attenuates the accumulation of potentially harmful byproducts of protein fermentation in the human colon.
我们研究了抗性淀粉（RS）对结肠蛋白质代谢标志物的影响。11名受试者参与了一项随机交叉研究，他们分别食用高抗性淀粉（39±3克/天，平均值±标准误）或低抗性淀粉（5±0.4克/天）饮食3周。所有其他常量营养素保持不变。在高抗性淀粉饮食期间，粪便氮的每日排泄量从1.84±0.15克/天增加到2.86±0.42克/天（P<0.01），粪便酚的排泄量从9.2±1.4毫克/天降至5.3±0.8毫克/天（P<0.01）。粪便中氨的浓度从397±33微克/克降至278±49微克/克（P<0.01），酚从69±8微克/克降至39±10微克/克（P<0.001）。尿氨、尿素、酚和总氮的每日排出量没有显著变化，但在高抗性淀粉期间，尿液pH值从6.4±0.1降至6.2±0.1（P<0.05）。这些结果表明，抗性淀粉可显著减少人体结肠中蛋白质发酵潜在有害副产物的积累。
