奥利韦罗斯病毒的特性，塔卡里比病毒复合体（沙粒病毒科：沙粒病毒属）的一个新成员

Characterization of Oliveros virus, a new member of the Tacaribe complex (Arenaviridae: Arenavirus).

作者信息

Mills J N, Barrera Oro J G, Bressler D S, Childs J E, Tesh R B, Smith J F, Enria D A, Geisbert T W, McKee K T, Bowen M D, Peters C J, Jahrling P B

机构信息

National Center for Infectious Diseases, Centers for Disease Control and Prevention, Atlanta, Georgia, USA.

出版信息

Am J Trop Med Hyg. 1996 Apr;54(4):399-404. doi: 10.4269/ajtmh.1996.54.399.

DOI:10.4269/ajtmh.1996.54.399

PMID:8615455

Abstract

Oliveros virus is an agent isolated in cell culture from Bolomys obscurus (Rodentia, Muridae, Sigmodontinae) captured on the central Argentine pampa. Oliveros virus was shown to be related to members of the Tacaribe complex of the family Arenaviridae by immunofluorescent antibody (IFA) tests, electrophoretic pattern of viral proteins, and morphology as observed by electron microscopy. It was distinct from 12 other arenaviruses by a combination of plaque-reduction neutralization tests, comparison of endpoint titers among cross-IFA tests, and comparison of viral RNA sequence data. This agent is the third new arenavirus from South America described within the last three years.

摘要

奥利韦罗斯病毒是从捕获于阿根廷中部潘帕斯草原的暗色稻鼠（啮齿目、鼠科、稻鼠亚科）的细胞培养物中分离出的一种病原体。通过免疫荧光抗体（IFA）试验、病毒蛋白的电泳图谱以及电子显微镜观察到的形态学，奥利韦罗斯病毒被证明与沙粒病毒科塔卡里贝病毒复合体的成员有关。通过蚀斑减少中和试验、交叉免疫荧光试验终点滴度的比较以及病毒RNA序列数据的比较，它与其他12种沙粒病毒不同。这种病原体是过去三年内在南美洲描述的第三种新型沙粒病毒。