Blumberg N, Kirkley S A, Heal J M
Department of Pathology, University of Rochester Medical Center, New York, USA.
Am J Surg. 1996 Mar;171(3):324-30. doi: 10.1016/S0002-9610(97)89635-3.
To analyze the cost consequences of autologous versus allogeneic transfusions.
Costs were determined when allogeneic transfusions were given in addition to, or instead of, autologous transfusions. Hospital charges were used to estimate costs for hip-replacement surgery. The main outcome measure was estimated incremental hospital costs per unit transfused.
Among donors of autologous blood, mean total charges were $7,200 greater for recipients of both autologous and allogeneic transfusions than for recipients of autologous transfusion only (P=0.0001). Each allogeneic transfusion was associated with additional costs of $1,480. In a second cohort of patients receiving identical amounts of either allogeneic or autologous blood (mean=2.3 units), total hospital charges were a mean of $4,800 greater (P=0.0001) for allogeneic recipients. The per unit excess costs associated with each unit of allogeneic blood cohort were $1,043.
Allogeneic transfusions are associated with incremental hospital costs of about $1,000 to $1,500 per unit transfused when compared with costs for similar patients receiving no transfusions or 1 to 5 units of autologous blood.
分析自体输血与异体输血的成本后果。
确定在给予异体输血作为自体输血的补充或替代时的成本。使用医院收费来估计髋关节置换手术的成本。主要结局指标是估计每单位输注的增量医院成本。
在自体血捐献者中，接受自体输血和异体输血的受者的平均总费用比仅接受自体输血的受者高7200美元（P = 0.0001）。每次异体输血会带来1480美元的额外费用。在另一组接受相同数量异体血或自体血（平均 = 2.3单位）的患者中，异体输血受者的医院总费用平均高出4800美元（P = 0.0001）。与每单位异体血相关的每单位额外费用为1043美元。
与未输血或接受1至5单位自体血的类似患者相比，异体输血每单位输注会带来约1000至1500美元的增量医院成本。
