Min Ji-Kang, Zhang Qiang-Hua, Li Hai-Dong, Li Heng, Guo Pan
From the Department of Orthopaedics, The First People's Hospital of Huzhou, Huzhou, Zhe Jiang Province, China.
Medicine (Baltimore). 2016 May;95(19):e3435. doi: 10.1097/MD.0000000000003435.
The blood loss during total hip arthroplasty is difficult to manage and there is no consensus about the effect of bipolar sealer used during operation. Thus, a systematic review of randomized controlled trials (RCTs) was performed to evaluate the efficacy and safety of blood loss using bipolar sealer after total hip arthroplasty (THA).Relevant literature of comparisons of bipolar sealer after THA for blood loss were searched for in Embase, PubMed, Web of Science, the Cochrane Central Register of Controlled Trials, and Google scholar from their inception to October, 2015. High-quality RCTs were selected to evaluate the need for transfusion, blood loss, and other complications. The software RevMan 5.30 was used for the meta-analysis.Six studies reporting on 6 RCTs comprising 751 patients were included. Compared with standard electrocautery, bipolar sealer was associated with lower rates of need for transfusion (relative risk [RR] = 0.60; 95% confidence interval [CI] 0.39-0.94), estimated blood loss (mean differences [MD] = -127.39; 95% CI -233.32 to -21.46; P = 0.02), and lower total blood loss (MD = -226.57; 95% CI -350.80-102.34; P = 0.0004). There is no significant difference between the hemoglobin drop, blood loss in drainage, intraoperative blood loss, Harris score, and rates of infection.The present meta-analysis indicated that bipolar sealer can decrease the need for transfusion and total blood loss; however, there is no benefit of bipolar sealer from the recovery. It is still need for samples to determine the balance between the economic cost and transfusion.
全髋关节置换术中的失血难以控制,对于手术中使用双极电凝器的效果也尚无共识。因此,进行了一项随机对照试验(RCT)的系统评价,以评估全髋关节置换术(THA)后使用双极电凝器对失血控制的有效性和安全性。从Embase、PubMed、Web of Science、Cochrane对照试验中心注册库以及谷歌学术中检索了自创建至2015年10月期间关于THA后使用双极电凝器减少失血的相关比较文献。选择高质量的RCT来评估输血需求、失血量及其他并发症。使用RevMan 5.30软件进行荟萃分析。纳入了6项研究,报告了6项RCT,共751例患者。与标准电灼术相比,双极电凝器组的输血需求率较低(相对危险度[RR]=0.60;95%置信区间[CI]0.39 - 0.94),估计失血量较少(平均差值[MD]= - 127.39;95% CI - 233.32至 - 21.46;P = 0.02),总失血量也较少(MD = - 226.57;95% CI - 350.80 - 102.34;P = 0.0004)。血红蛋白下降、引流量、术中失血量、Harris评分及感染率之间无显著差异。本荟萃分析表明,双极电凝器可减少输血需求和总失血量;然而,双极电凝器在恢复方面并无益处。仍需要更多样本以确定经济成本与输血之间的平衡。