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头颈部癌症患者的生活质量和功能状态测量

Quality of life and functional status measures in patients with head and neck cancer.

作者信息

D'Antonio L L, Zimmerman G J, Cella D F, Long S A

机构信息

School of Medicine, Loma Linda University, Calif, USA.

出版信息

Arch Otolaryngol Head Neck Surg. 1996 May;122(5):482-7. doi: 10.1001/archotol.1996.01890170018005.

Abstract

OBJECTIVE

To assess the relationship among three validated head and neck-specific measures of functional status and a general measure of quality of life in patients with head and neck cancer.

DESIGNS

Cross-sectional study using medical chart review, patient interview, and test administration.

SETTING

Academic tertiary referral center.

PARTICIPANTS

Fifty adults patients 3 months to 6 years after major surgery for head and neck cancer.

MAIN OUTCOME MEASURE

Scores from a general measure of quality of life (the Functional Assessment of Cancer Therapy), a subscale specific to head and neck cancer, the University of Washington Quality of Life Questionnaire, and the Performance Status Scale for Head and Neck Cancer Patients.

RESULTS

The disease-specific measures of functional status correlate well with one another. However, there were low correlations between the Functional Assessment of Cancer Therapy and the disease-specific measures, indicating that general and disease-specific instruments contribute unique information about quality of life.

CONCLUSION

A general measure of quality of life augments information obtained by disease-specific instruments by interpreting functional status in the broader scope of the patient's life.

摘要

目的

评估三种经过验证的头颈部特定功能状态测量指标与头颈部癌症患者总体生活质量测量指标之间的关系。

设计

采用病历回顾、患者访谈和测试管理的横断面研究。

地点

学术三级转诊中心。

参与者

50名成年患者,在接受头颈部癌症大手术后3个月至6年。

主要观察指标

来自总体生活质量测量指标(癌症治疗功能评估)、头颈部癌症特定子量表、华盛顿大学生活质量问卷以及头颈部癌症患者体能状态量表的得分。

结果

特定疾病的功能状态测量指标之间相互关联良好。然而,癌症治疗功能评估与特定疾病测量指标之间的相关性较低,这表明总体和特定疾病的测量工具提供了关于生活质量的独特信息。

结论

总体生活质量测量指标通过在患者生活的更广泛范围内解释功能状态,增强了特定疾病测量工具所获得的信息。

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