Conigrave K M, Hall W D, Saunders J B
Centre for Drug and Alcohol Studies, Royal Prince Alfred Hospital, New South Wales, Australia.
Addiction. 1995 Oct;90(10):1349-56. doi: 10.1046/j.1360-0443.1995.901013496.x.
The Alcohol Use Disorders Identification Test (AUDIT) is a 10-item questionnaire designed by the World Health Organization to screen for hazardous alcohol intake in primary health care settings. In this longitudinal study we examined its performance in predicting alcohol-related harm over the full range of its scores using receiver operating characteristic analyses. Three hundred and thirty ambulatory care patients were interviewed using a detailed assessment schedule which included the AUDIT questions. After 2-3 years, subjects were reviewed and their experience of alcohol-related medical and social harm assessed by interview and perusal of medical records. AUDIT was a good predictor of both alcohol-related social and medical problems. Cut-off points of 7-8 maximized discrimination in the prediction of trauma and hypertension. Higher cut-offs (12 and 22) provided better discrimination in the prediction of alcohol-related social problems and of liver disease or gastrointestinal bleeding, but high specificity was offset by reduced sensitivity. We conclude that the recommended cut-off score of eight is a reasonable approximation to the optimal for a variety of endpoints.
酒精使用障碍识别测试（AUDIT）是世界卫生组织设计的一份包含10个条目的问卷，用于在初级卫生保健机构中筛查有害饮酒情况。在这项纵向研究中，我们使用受试者工作特征分析，考察了该测试在其整个分数范围内预测酒精相关危害的表现。我们使用一份详细的评估表对330名门诊患者进行了访谈，该评估表包括AUDIT的问题。2至3年后，对受试者进行复查，并通过访谈和查阅病历评估他们与酒精相关的医疗和社会危害经历。AUDIT是酒精相关社会问题和医疗问题的良好预测指标。7至8分的截断点在预测创伤和高血压方面能最大限度地提高辨别力。更高的截断点（12分和22分）在预测酒精相关社会问题以及肝病或胃肠道出血方面能提供更好的辨别力，但高特异性被敏感性降低所抵消。我们得出结论，推荐的8分截断分数是各种终点最优值的合理近似值。
