Lawrence W T, Banes A J
Division of Plastic Surgery, University of Massachusetts Medical Center, Worcester, USA.
Clin Plast Surg. 1996 Jan;23(1):173-82.
Several areas of plastic surgery research, both in and out of the basic science laboratory, have been highlighted. Progress is being made in our ability to produce biologic structures to replace destroyed or damaged ones in vitro, our ability to manipulate the genetic structure of cells, and our ability to define and potentially manipulate the wound healing process in normal and abnormal healing states. More is also being learned about the biology of nerve repair, the physiologic response to silicone implants, and the mechanism of reperfusion injury. Virtual surgery may become a major part of the planning, performance, and teaching of surgical procedures in the future. Outcomes need to be better defined to prove the value of what plastic surgeons do to increasingly skeptical third parties, and progress is being made in this area as well. These areas represent only a few aspects of what is new in plastic surgery research, but they at least provide a window into the field and demonstrate the increasing sophistication of work being done in all areas. This work, as well as work in other areas, will undoubtedly affect clinical practices in the near future.
整形外科学研究的几个领域，无论是在基础科学实验室内部还是外部，都已得到重点关注。我们在体外制造生物结构以替代受损或毁坏结构的能力、操纵细胞基因结构的能力，以及在正常和异常愈合状态下定义并潜在操纵伤口愈合过程的能力都取得了进展。我们对神经修复生物学、硅酮植入物的生理反应以及再灌注损伤机制也有了更多了解。虚拟手术未来可能会成为手术程序规划、实施和教学的重要组成部分。需要更好地界定结果，以向越来越持怀疑态度的第三方证明整形外科医生工作的价值，这方面也正在取得进展。这些领域仅代表整形外科学研究新进展的几个方面，但它们至少为该领域提供了一个窗口，并展示了所有领域工作日益复杂的情况。这项工作以及其他领域的工作无疑将在不久的将来影响临床实践。
