Kodama M, Tur G E, Shiozawa N, Koyama K
Department of Surgery, Akita University School of Medicine, Japan.
J Surg Oncol. 1996 May;62(1):57-61. doi: 10.1002/(SICI)1096-9098(199605)62:1<57::AID-JSO12>3.0.CO;2-Q.
The clinicopathological features of multiple primary gastric carcinoma in 107 patients who had undergone gastrectomy between 1972 and 1992 were studied and compared with those of single gastric carcinoma in 1,456 patients. The incidence of occurrence of multiple primary gastric carcinoma was 6.8% of patients who had gastrectomy for gastric cancer. Such carcinoma was detected less often in patients <49 years of age. Dominant findings involved an elevated gross appearance, papillary or well-differentiated adenocarcinoma in the histology, and invasion to the depth of mucosa. When multiple primary gastric carcinoma was classified by main and concomitant lesions based on the stage of the disease, concomitant lesions were detected more often in the lower third of the stomach and at the distal site of main lesions located in the upper or middle third of the stomach. These results indicate that the lower third of the stomach and the distal site of the main lesion must be investigated carefully to ensure that incidental concomitant lesions are not overlooked, especially when a patient has the clincopathological features described above.
对1972年至1992年间接受胃切除术的107例多原发性胃癌患者的临床病理特征进行了研究，并与1456例单发性胃癌患者的临床病理特征进行了比较。多原发性胃癌的发生率占因胃癌接受胃切除术患者的6.8%。49岁以下患者中这种癌症的检出率较低。主要表现为大体外观隆起，组织学上为乳头状或高分化腺癌，侵犯至黏膜层。根据疾病分期将多原发性胃癌分为主要病变和伴随病变时，伴随病变在胃下1/3以及位于胃上1/3或中1/3的主要病变的远端部位更常被检测到。这些结果表明，必须仔细检查胃下1/3和主要病变的远端部位，以确保不遗漏偶然的伴随病变，尤其是当患者具有上述临床病理特征时。
