Urano A
Cell Tissue Res. 1977 Apr 20;179(3):331-45. doi: 10.1007/BF00221104.
Changes in the activity of monoamine oxidase (MAO) and acetylcholinesterase (AChE) following unilateral eye enucleation were measured for the superior colliculus (SC), lateral geniculate body (LGB), and nucleus suprachiasmaticus (NSC) in the rat by means of microspectrophotometry. The most conspicuous change of high significance was the decrease of MAO activity in the superficial strata of the SC contralateral to the enucleated eye. The other layers of SC, such as the stratum opticum, the intermediate strata, the deep strata and the central gray did not show significant postoperative changes in MAO acitivity. MAO activity of the LGB and the NSC was also not affected to a significant degree. The site of decrease of MAO activity in the superficial strata of the SC sould be degenerating optic nerve terminals. The strong AChE activity in the superficial strata may be derived from the horizontal cells. AChE activity in the SC showed only slight postoperative changes. The possible roles of the monoaminergic and cholinergic systems in the process of visual information are discussed.
通过显微分光光度法测量了单侧眼球摘除后大鼠上丘（SC）、外侧膝状体（LGB）和视交叉上核（NSC）中，单胺氧化酶（MAO）和乙酰胆碱酯酶（AChE）活性的变化。最显著且具有高度统计学意义的变化是，摘除眼球对侧上丘表层的MAO活性降低。上丘的其他层，如视层、中间层、深层和中央灰质，术后MAO活性未显示出显著变化。外侧膝状体和视交叉上核的MAO活性也未受到显著影响。上丘表层MAO活性降低的部位可能是正在退化的视神经终末。表层强烈的AChE活性可能来自水平细胞。上丘中的AChE活性术后仅显示出轻微变化。讨论了单胺能和胆碱能系统在视觉信息处理过程中的可能作用。
