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[使用热成像方法评估皮肤点刺试验。I. 进行皮肤点刺试验区域的背景温度。液晶记录的温度差异的最佳色标及其使用条件]

[Use of thermography methods for evaluating skin prick tests. I. Background temperature of area where skin prick tests are performed. Optimal color scale of temperature differences registered by liquid crystals and conditions of their use].

作者信息

Kruszewski J, Zuber J, Zmija J, Kłosowicz S, Sacha P, Lukasiewicz J

机构信息

Kliniki Chorób Infekcyjnych i Alergologii, Cenralnego Szpitala Klinicznego WAM w Warszawie.

出版信息

Pneumonol Alergol Pol. 1995;63(9-10):507-15.

PMID:8620171
Abstract

The aim of the study was to estimate the value in visualization of temperature gradients in assessing results of skin prick tests. The study group consisted of 10 patients suspected of having allergic diseases in whom skin prick tests were carried out. They were performed typically using the Bencard allergens kits. A positive control was performed using different solutions of histamine (10 mg/ml, 1 mg/ml, 0.1 mg/ml). The traditional method comprising of measurement of erythema, and whed was compared with visual thermography and open liquid crystal themography. The background temperature of typical areas chosen for skin prick tests were compared under condition of thermographic evaluation. The skin of the upper region of the back was chosen for uniform temperature background. Basing on the analysis of the background temperature and in areas of high reaction to histamine and allergens the temperature and in areas of high reaction to histamine and allergens the temperature gradient was calculated to be 2.2 degrees--2.5 degrees C. In order to visualize this gradient in composition of liquid crystals was made of a working range of 34.3 degrees--36.3 degrees C. Criteria for a correct thermographic evaluation of skin prick tests were established after studying the effect of manipulation of the area examined, local lowering of the temperature, use of cold solutions of allergens. Further studies are planned in order to assess the practical use of this thermographic analytical method.

摘要

本研究的目的是评估温度梯度可视化在评估皮肤点刺试验结果中的价值。研究组由10名疑似患有过敏性疾病且接受了皮肤点刺试验的患者组成。这些试验通常使用本卡德过敏原试剂盒进行。使用不同浓度的组胺溶液(10mg/ml、1mg/ml、0.1mg/ml)进行阳性对照。将测量红斑的传统方法与视觉热成像和开放式液晶热成像进行比较。在热成像评估条件下,比较了皮肤点刺试验所选典型区域的背景温度。选择背部上方区域的皮肤作为温度均匀的背景。基于对背景温度的分析以及对组胺和过敏原高反应区域的分析,计算出温度梯度为2.2摄氏度至2.5摄氏度。为了可视化该梯度,制作了工作范围为34.3摄氏度至36.3摄氏度的液晶组合物。在研究了对检查区域的操作、局部降温、使用过敏原冷溶液的效果后,建立了皮肤点刺试验热成像正确评估的标准。计划进行进一步研究以评估这种热成像分析方法的实际应用。

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