Vinogradov V V, Mandrik K A, Larin F S, Buko V U, Pavlenia A K
Vopr Pitan. 1979 Mar-Apr(2):34-40.
An investigation into the total lipids, fatty acids, total phospholipids and ATP content in the liver of rats given nicotinamide, separately and together with hydrocortisone, showed that the disclosed shifts mutually correlate well and may be explained in keeping within the bounds of the idea as to the lipotropic action of the preparations. The coincidence of the corticosteroids and nicotinamide effects in regards to mobilization of lipids and their oxidation in the liver presumes a hormonal causation of shifts on the level of lipids metabolism.
对分别给予烟酰胺以及烟酰胺与氢化可的松联合使用的大鼠肝脏中的总脂质、脂肪酸、总磷脂和ATP含量进行的一项研究表明,所发现的变化相互之间具有良好的相关性,并且可以在关于这些制剂的促脂作用的观点范围内得到解释。皮质类固醇和烟酰胺在肝脏脂质动员及其氧化方面的作用巧合,推测脂质代谢水平的变化存在激素因果关系。