[肾上腺切除术及皮质醇给药对大鼠肝脏游离脂肪酸、甘油三酯和总脂质浓度的影响]
[Effects of adrenalectomy and cortisol administration on the concentration of free fatty acids, triglycerides and total lipids on the liver of rats].
作者信息
De Gandarias J M, Lacort M, Fernández B, Rabanal S, Ainz F, Pamo J M, Goiriena de Gandarias J J
出版信息
Rev Iber Endocrinol. 1976;23(136):371-83.
The hepatic concentration of triglycerides, free fatty acids and total lipids was determined in four groups of rats: normals, adrenectomized and normal and adrenectomized previously treated with cortisol, 30 mg. In chronic adrenectomized state, total lipids and hepatic triglycerides are diminished, particularly the triglycerides. Adrenectomy does not appear to have significative effect on the free fatty acids. The administration of cortisol does not change those observations and, when given to normal animals, decreases the hepatic concentrations of free fatty acids, triglycerides and total lipids.
测定了四组大鼠肝脏中甘油三酯、游离脂肪酸和总脂质的浓度：正常大鼠、肾上腺切除大鼠以及术前用30毫克皮质醇处理过的正常和肾上腺切除大鼠。在慢性肾上腺切除状态下，总脂质和肝脏甘油三酯减少，尤其是甘油三酯。肾上腺切除术似乎对游离脂肪酸没有显著影响。给予皮质醇并不会改变这些观察结果，并且当给予正常动物时，会降低肝脏中游离脂肪酸、甘油三酯和总脂质的浓度。
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