Molecular anatomy and the pathological expression of antibody light chains.
作者信息
Schiffer M
机构信息
Center for Mechanistic Biology and Biotechnology, Argonne National Laboratory, Illinois 60439, USA.
出版信息
Am J Pathol. 1996 May;148(5):1339-44.
Abstract
摘要
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本文引用的文献
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Am J Pathol. 1996 May;148(5):1397-406.
2
Destabilizing effects of replacing a surface lysine of cytochrome c with aromatic amino acids: implications for the denatured state.用芳香族氨基酸取代细胞色素c表面赖氨酸的去稳定化作用：对变性状态的影响
Biochemistry. 1993 Jan 12;32(1):183-90. doi: 10.1021/bi00052a024.
3
Expressed human immunoglobulin kappa genes and their hypermutation.表达的人类免疫球蛋白κ基因及其超突变
Eur J Immunol. 1993 Dec;23(12):3248-62. doi: 10.1002/eji.1830231231.
4
A role for destabilizing amino acid replacements in light-chain amyloidosis.不稳定氨基酸替代在轻链淀粉样变性中的作用。
Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5446-50. doi: 10.1073/pnas.91.12.5446.
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Identification and characterization of a functional human Ig V lambda VI germline gene.功能性人类Ig VλVI种系基因的鉴定与表征
Mol Immunol. 1994 May;31(7):531-6. doi: 10.1016/0161-5890(94)90040-x.
6
Pathogenic potential of human monoclonal immunoglobulin light chains: relationship of in vitro aggregation to in vivo organ deposition.人单克隆免疫球蛋白轻链的致病潜力：体外聚集与体内器官沉积的关系。
Proc Natl Acad Sci U S A. 1994 Apr 12;91(8):3034-8. doi: 10.1073/pnas.91.8.3034.
7
Sequence statistics reliably predict stabilizing mutations in a protein domain.序列统计能够可靠地预测蛋白质结构域中的稳定突变。
J Mol Biol. 1994 Jul 15;240(3):188-92. doi: 10.1006/jmbi.1994.1434.
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Comparison of crystal structures of two homologous proteins: structural origin of altered domain interactions in immunoglobulin light-chain dimers.两种同源蛋白质晶体结构的比较：免疫球蛋白轻链二聚体中结构域相互作用改变的结构起源。
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Protein Sci. 1995 Mar;4(3):421-32. doi: 10.1002/pro.5560040309.
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