Masár O, Zelinková M, Pechan J, Krcméry S, Hanusková D, Buzukasvili M
Anestéziologicko-resuscitacné oddelenie, II. chirurgická klinika LFUK, Bratislave.
Bratisl Lek Listy. 1995 Dec;96(12):669-70.
Postoperative analgesia inhibits the stress cascade with negative effects on whole organism. Therefore the spectrum of drugs used for soothing postoperative pain quickly widens. The epidural route appears as being logical, since due to the direct effect in the transmission and processing of pain it suffices with a lower dosage. The authors refer to a group of 30 patients postoperatively treated by a combination of tramadol and Clonidine administrated by means of an epidural catheter. 26 patients evaluated the induced analgesia as excellent or sufficient. (Tab. 3, Ref. 4).
术后镇痛可抑制应激反应,对整个机体产生负面影响。因此,用于快速缓解术后疼痛的药物种类迅速增加。硬膜外途径似乎是合理的,因为由于其对疼痛传递和处理的直接作用,较低剂量就足够了。作者提到一组30例术后患者,通过硬膜外导管联合使用曲马多和可乐定进行治疗。26例患者将诱导的镇痛效果评价为优或良。(表3,参考文献4)