Sanders E J, Tukei P M
Virus Research Centre, Kenya Medical Research Institute, Nairobi, Kenya.
East Afr Med J. 1996 Jan;73(1):10-2.
Yellow fever (YF) is a well known disease that had plagued the tropics relentlessly until an effective vaccine was developed. Although the yellow fever vaccine is relatively affordable and one dose protects for over ten years, its use has predominantly been for known endemic areas of the world and international travellers. Eastern and southern African states, have hitherto been free of epidemic yellow fever, hence routine YF vaccination is not a policy in these countries. The sudden emergence of YF in the Rift Valley in Kenya in 1992-1993, introduces new dimensions into the challenges of YF to eastern and southern African states. Isolation of a virus deemed to be native of the area is discussed in this article in the context of YF policy issues confronting the region. A case has been argued for the establishment of a network of active surveillance systems in the region backed by adequate laboratory YF expertise locally, regionally, and internationally.
黄热病是一种众所周知的疾病，在有效疫苗研发出来之前，它一直无情地肆虐着热带地区。尽管黄热病疫苗相对价格低廉，且一剂疫苗的保护期超过十年，但其使用主要集中在世界上已知的流行地区和国际旅行者身上。东非和南非国家迄今没有出现过黄热病流行，因此在这些国家，常规的黄热病疫苗接种并非一项政策。1992年至1993年期间，黄热病在肯尼亚裂谷地区突然出现，为东非和南非国家应对黄热病挑战带来了新的层面。本文在该地区面临的黄热病政策问题背景下，讨论了一种被认为原产于该地区的病毒的分离情况。有人主张在该地区建立一个由当地、区域和国际上足够的黄热病实验室专业知识支持的主动监测系统网络。
