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[波兰羟乙基淀粉制剂:一项临床研究]

[Polish hydroxyethyl starch preparation: a clinical study].

作者信息

Schier J, Kościelak J, Szczepanik A, Gryszkiewicz A, Lopaciuk S, Konopka L, Rudowski W

出版信息

Acta Haematol Pol. 1979 Jan-Mar;10(1):51-8.

PMID:86269
Abstract

The 6% solution of hydroxyethyl starch (MS = 0.47-0.7, Mw = 120,000-220,000) prepared at the Department of Biochemistry, Institute of Haematology in Warsaw was administered in infusions to a group of surgical patients. It was found that the preparation complied with the conditions and requirements for plasma-replacing agents. In none of the treated patients any side effects were observed. Further investigations will be continued infusing greater volumes of HES to patients with hypovolaemia of different origin.

摘要

由华沙血液学研究所生物化学系制备的6%羟乙基淀粉溶液(MS = 0.47 - 0.7,Mw = 120,000 - 220,000)通过静脉输注给予一组外科手术患者。结果发现该制剂符合血浆代用品的条件和要求。在所有接受治疗的患者中均未观察到任何副作用。进一步的研究将继续对不同病因的低血容量患者输注更大剂量的羟乙基淀粉。

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