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迟发性皮肤卟啉症中铁和卟啉在肝脏中的定位。

Location of iron and porphyrin in the liver in porphyria cutanea tarda.

作者信息

Petryka Z J, Kostich N D, Dhar G J

出版信息

Acta Histochem. 1978;63(2):168-76. doi: 10.1016/s0065-1281(78)80022-1.

Abstract

Porphyrin and iron distributions in the liver biopsies of patients with Porphyria cutanea tarda (PCT) were investigated by comparison of composite photographs from fluorescence microscope and after iron stain. Three distinct areas are visible: 1. red fluorescent areas with porphyrins; 2. blue areas corresponding to iron; 3. areas with neither iron nor porphyrin. The areas with iron or porphyrin do not overlap, therefore, this experiment indicates lack of direct correlation between iron and prophyrin distribution in livers of PCT patients.

摘要

通过比较荧光显微镜下的合成照片以及铁染色后的照片,对迟发性皮肤卟啉病(PCT)患者肝活检中的卟啉和铁分布进行了研究。可观察到三个不同区域:1. 含卟啉的红色荧光区域;2. 对应铁的蓝色区域;3. 既不含铁也不含卟啉的区域。含铁或卟啉的区域不重叠,因此,该实验表明PCT患者肝脏中铁与卟啉分布之间缺乏直接相关性。

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Iron metabolism in porphyria cutanea tarda.
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引用本文的文献

1
The role of iron in experimental porphyria and porphyria cutanea tarda.
Biol Trace Elem Res. 1992 Oct;35(1):65-72. doi: 10.1007/BF02786238.

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