Sillero-Zubiri C
Zoology Department, Oxford University, United Kingdom.
J Wildl Dis. 1996 Jan;32(1):147-51. doi: 10.7589/0090-3558-32.1.147.
Telazol (tiletamine hydrochloride and zolazepam hydrochloride combination) and a combination of ketamine hydrochloride and acepromazine were used to immobilize wild Ethiopian wolves (Canis simensis) in Ethiopia from 1988 to 1992. Telazol doses of 2.1 to 6.5 mg/kg resulted in a mean (+/- SD) induction time of 2.3 +/- 0.9 min and a mean (+/- SD) immobilization time of 82.2 +/- 28.6 min. Induction time did not differ by dose, wolf weight, or age, but was significantly longer for females. Immobilization time differed with dose, but not by wolf weight, age, or sex. Total recovery times ranged from 50 to 158 min. There were no apparent side effects on immobilized animals. Wolves immobilized using a combination of ketamine hydrochloride and acetylpromazine had longer induction time (3.0 +/- 0.8 min) and recovery time (114.7 +/- 29.2 min). Telazol is an effective and safe agent for immobilizing Ethiopian wolves and is preferred to ketamine/acetylpromazine.
1988年至1992年期间，在埃塞俄比亚，替来他明（盐酸替来他明与盐酸唑拉西泮的复方制剂）以及盐酸氯胺酮与乙酰丙嗪的复方制剂被用于麻醉野生埃塞俄比亚狼（西门豺）。替来他明剂量为2.1至6.5毫克/千克时，平均（±标准差）诱导时间为2.3±0.9分钟，平均（±标准差）麻醉时间为82.2±28.6分钟。诱导时间不受剂量、狼的体重或年龄影响，但雌性狼的诱导时间显著更长。麻醉时间因剂量而异，但不受狼的体重、年龄或性别影响。总恢复时间为50至158分钟。对麻醉的动物未观察到明显副作用。使用盐酸氯胺酮与乙酰丙嗪复方制剂麻醉的狼诱导时间（3.0±0.8分钟）和恢复时间（114.7±29.2分钟）更长。替来他明是麻醉埃塞俄比亚狼的一种有效且安全的药物，优于氯胺酮/乙酰丙嗪。
