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埃塞俄比亚狼(西门豺)的狂犬病与死亡率

Rabies and mortality in Ethiopian wolves (Canis simensis).

作者信息

Sillero-Zubiri C, King A A, Macdonald D W

机构信息

Wildlife Conservation Research Unit, Zoology Department, Oxford, United Kingdom.

出版信息

J Wildl Dis. 1996 Jan;32(1):80-6. doi: 10.7589/0090-3558-32.1.80.

Abstract

Between October 1991 and February 1992, 41 of 53 known adult and subadult Ethiopian wolves (Canis simensis) in five adjacent packs in the Bale Mountains National Park, Ethiopia, died or disappeared. Brain smears from two carcasses were positive for rabies by the immunofluorescence test, and rabies virus was isolated from the brains by mouse inoculation. Based on monoclonal antibody tests on the mouse brains, we identified the virus as a minor variant of the serotype 1 rabies viruses found in domestic dogs and wild canids of Africa. Sera from two of 15 Ethiopian wolves had rabies virus neutralizing antibody.

摘要

1991年10月至1992年2月期间,埃塞俄比亚巴勒山国家公园五个相邻狼群中已知的53只成年和亚成年埃塞俄比亚狼(西门豺)中有41只死亡或失踪。对两具尸体的脑涂片进行免疫荧光试验,结果显示狂犬病呈阳性,通过小鼠接种从脑中分离出狂犬病病毒。基于对小鼠脑的单克隆抗体检测,我们将该病毒鉴定为在非洲家犬和野生犬科动物中发现的1型狂犬病病毒的一个小变种。15只埃塞俄比亚狼中有两只的血清含有狂犬病病毒中和抗体。

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