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采用酶联免疫吸附测定法(ELISA)和快速荧光灶抑制试验(RFFIT)检测未接种疫苗的犬类以及埃塞俄比亚濒危的西门豺(Canis simensis)体内的狂犬病抗体。

Detection of rabies antibody by ELISA and RFFIT in unvaccinated dogs and in the endangered Simien jackal (Canis simensis) of Ethiopia.

作者信息

Mebatsion T, Sillero-Zubiri C, Gottelli D, Cox J H

机构信息

National Research Institute of Health, Addis Ababa, Ethiopia.

出版信息

Zentralbl Veterinarmed B. 1992 May;39(3):233-5. doi: 10.1111/j.1439-0450.1992.tb01162.x.

DOI:10.1111/j.1439-0450.1992.tb01162.x
PMID:1642078
Abstract

Varying levels of rabies antibody have been detected both by Enzyme Linked Immunosorbent Assay (ELISA) and Rapid Fluorescent Focus Inhibition Test (RFFIT) in the sera collected from wild and domestic canids in the Bale Mountains National Park (BMNP) of Southern Ethiopia. Rabies antibody was detected in 80% (8 out of 10) of domestic dog samples, 13.3% (2 out of 15) of Simien jackal samples and in one common jackal. Rabies virus was isolated from one dog in an area where contact with the Simien jackal could possibly occur. All samples examined from wild rodents as possible reservoir hosts for rabies were found negative. The presence of large proportion of susceptible Simien jackals in the population should be a cause of great concern in saving this endangered species from the ravages of rabies.

摘要

通过酶联免疫吸附测定(ELISA)和快速荧光灶抑制试验(RFFIT),在从埃塞俄比亚南部巴勒山国家公园(BMNP)的野生和家养犬科动物采集的血清中检测到了不同水平的狂犬病抗体。在家养狗样本中,80%(10份样本中的8份)检测到狂犬病抗体,西门豺样本中有13.3%(15份样本中的2份)检测到狂犬病抗体,一只金背胡狼样本中也检测到狂犬病抗体。在一个可能与西门豺接触的地区,从一只狗身上分离出了狂犬病病毒。所有作为狂犬病可能储存宿主的野生啮齿动物样本检测均为阴性。该种群中存在很大比例易感染狂犬病的西门豺,这对于保护这种濒危物种免受狂犬病侵害来说,应引起高度关注。

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