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泪腺原发性导管腺癌

Primary ductal adenocarcinoma of the lacrimal gland.

作者信息

Katz S E, Rootman J, Dolman P J, White V A, Berean K W

机构信息

Department of Ophthalmology, Vancouver Hospital & Health Sciences Centre, Canada.

出版信息

Ophthalmology. 1996 Jan;103(1):157-62. doi: 10.1016/s0161-6420(96)30746-x.

DOI:10.1016/s0161-6420(96)30746-x
PMID:8628547
Abstract

PURPOSE

To their knowledge, the authors report the first recognized case of ductal adenocarcinoma of the lacrimal gland (histologic equivalent of salivary duct carcinoma). Primary adenocarcinoma of the lacrimal gland is rare and has been described generically. In contrast, primary adenocarcinomas of the major and minor salivary glands are much more common and have been classified into histopathologic subtypes that have different clinical characteristics and outcomes.

METHODS

A 68-year-old man presented with a 6-month history of a painless mass in the right upper outer eyelid. The authors describe the clinical, radiologic, and histopathologic features of this case and review the lacrimal gland literature.

RESULTS

A modified en bloc orbitectomy was performed, and postoperative radiotherapy was administered. The patient was alive and well without evidence of tumor recurrence 10 months after surgery.

CONCLUSION

The World Health Organization classification of salivary adenocarcinomas (1991) provides a framework for further insight into the presentation and biologic behavior of the less common lacrimal carcinomas.

摘要

目的

据作者所知,他们报告了首例被认可的泪腺导管腺癌病例(组织学上等同于涎腺导管癌)。泪腺原发性腺癌较为罕见,此前仅有一般性描述。相比之下,大、小涎腺的原发性腺癌更为常见,且已被分为具有不同临床特征和预后的组织病理学亚型。

方法

一名68岁男性患者,右上外侧眼睑出现无痛性肿块6个月。作者描述了该病例的临床、放射学和组织病理学特征,并对泪腺相关文献进行了回顾。

结果

实施了改良整块眼眶切除术,并进行了术后放疗。术后10个月,患者存活且状况良好,无肿瘤复发迹象。

结论

世界卫生组织(1991年)涎腺癌分类为深入了解较少见的泪腺癌的临床表现和生物学行为提供了一个框架。

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