Occelli E, Fontanella L, Testa E
Farmaco Sci. 1977 Apr;32(4):237-47.
As a part of research on 3,8-diazabicyclo [3,2,1] octanes, the Authors report on the synthesis of some amides of methyl, phenyl and cyclohexyltropic acid, potentially active as antiparkinson agents. Also reported is the synthesis of some compounds similar to two known drugs, Caramiphene and Cycrimine. These compounds differ from the said drugs in having a 3,8-diazabicyclo [3,2,1] octane as a basic moiety.
作为对3,8 - 二氮杂双环[3,2,1]辛烷研究的一部分，作者报道了一些甲基、苯基和环己基托品酸酰胺的合成，这些酰胺可能作为抗帕金森病药物具有活性。还报道了一些与两种已知药物卡拉米芬和环苯扎林类似的化合物的合成。这些化合物与上述药物的不同之处在于其具有3,8 - 二氮杂双环[3,2,1]辛烷作为基本部分。
