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成人体外膜肺氧合:影像学表现及肺实质密度与患者死亡率的相关性

Extracorporeal membrane oxygenation in adults: radiographic findings and correlation of lung opacity with patient mortality.

作者信息

Jamadar D A, Kazerooni E A, Cascade P N, Fazzalari F L, Vydareny K H, Bartlett R H

机构信息

Department of Radiology, University of Michigan Medical Center, Ann Arbor 48109-0326, USA.

出版信息

Radiology. 1996 Mar;198(3):693-8. doi: 10.1148/radiology.198.3.8628856.

Abstract

PURPOSE

To describe the radiographic appearance of extracorporeal membrane oxygenation (ECMO) in adults and to correlate lung opacity with physiologic parameters and mortality.

MATERIALS AND METHODS

Chest radiographs of 50 adults treated with ECMO were reviewed; pre-ECMO radiographs were available in 35 patients. Lung opacity was assigned a score of 0-4. Complications of ECMO seen at chest radiography were recorded.

RESULTS

The lung opacity scores of the first post-ECMO radiographs were higher than those of the pre-ECMO radiographs in 17 of 35 patients (P = .0005). Maximum opacity score was significantly lower for patients who survived compared with those who died (P = .001). Twelve of 14 patients (86%) with a maximum opacity score of 4 died, compared with eight of 29 patients (28%) with a maximum score of 3. Sixteen of 26 patients (61%) with evidence of baro-trauma died, compared with six of 24 patients (25%) without pneumothorax (P = .02). Four patients developed hemothorax.

CONCLUSION

Lung opacity increases immediately after initiation of ECMO. Increased opacity corresponds to decreased pulmonary function, and severe opacity correlates strongly with mortality.

摘要

目的

描述成人体外膜肺氧合(ECMO)的影像学表现,并将肺实质密度增高与生理参数及死亡率相关联。

材料与方法

回顾了50例接受ECMO治疗的成人患者的胸部X线片;35例患者有ECMO治疗前的X线片。肺实质密度增高情况分为0 - 4分。记录胸部X线片上显示的ECMO并发症。

结果

35例患者中,17例患者ECMO治疗后的首次胸部X线片上肺实质密度增高评分高于治疗前(P = .0005)。存活患者的最大密度增高评分显著低于死亡患者(P = .001)。最大密度增高评分为4分的14例患者中有12例(86%)死亡,而最大评分为3分的29例患者中有8例(28%)死亡。有气压伤证据的26例患者中有16例(61%)死亡,而无气胸的24例患者中有6例(25%)死亡(P = .02)。4例患者发生血胸。

结论

开始ECMO后肺实质密度立即增加。密度增加与肺功能下降相对应,严重的密度增高与死亡率密切相关。

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