Darcy M D, Kanterman R Y, Kleinhoffer M A, Vesely T M, Picus D, Hicks M E, Pilgram T K
Mallinckrodt Institute of Radiology, Washington University School of Medicine, St Louis, Missouri 63110, USA.
Radiology. 1996 Mar;198(3):741-4. doi: 10.1148/radiology.198.3.8628863.
To determine whether prothrombin time (PT), partial thromboplastin time (PTT), and platelet count are useful predictors of postangiographic hematoma.
The authors prospectively studied 1,000 consecutive patients who underwent femoral arterial puncture for a diagnostic or therapeutic vascular procedure. Demographic and procedural variables were recorded, including patient age and sex, history of medications and bleeding, procedure type and length, catheter size, and experience level of radiologist applying compression for hemostasis.
Abnormal results of coagulation tests were not correlated with an increased occurrence of hemorrhagic complications, but bleeding complications did occur more often in patients with thrombocytopenia. Hematomas occurred in 8.1% (10 of 123) of patients with any abnormal coagulation test results and 9.7% (85 of 877) of patients with normal test results. A platelet count of less than 100 X 10(9)/L was correlated with a higher occurrence of hematoma (P = .002).
Abnormal PT and PTTs do not correlate with an increased risk of postangiographic hematoma, but a low platelet count is associated with more bleeding complications.
确定凝血酶原时间（PT）、部分凝血活酶时间（PTT）和血小板计数是否为血管造影术后血肿的有效预测指标。
作者前瞻性研究了连续1000例因诊断或治疗性血管操作而接受股动脉穿刺的患者。记录人口统计学和操作变量，包括患者年龄和性别、用药及出血史、操作类型和时长、导管尺寸以及应用压迫止血的放射科医生的经验水平。
凝血试验结果异常与出血并发症发生率增加无关，但血小板减少患者出血并发症的发生确实更为频繁。任何凝血试验结果异常的患者中血肿发生率为8.1%（123例中的10例），试验结果正常的患者中血肿发生率为9.7%（877例中的85例）。血小板计数低于100×10⁹/L与较高的血肿发生率相关（P = 0.002）。
PT和PTT异常与血管造影术后血肿风险增加无关，但血小板计数低与更多出血并发症相关。
