Mazzone G, Pappalardo G
Farmaco Sci. 1977 May;32(5):348-54.
In continuation of previus research on the antimitotic activity of aryldisulfides, the Authors have synthesised 3- and 5-chloro or fluoro substituted bis-(2-aminophenyl)disulfides and some of their 2-N-alkyl derivatives. These compounds were synthesised in order to submit them to biological testing to find any activity caused by halogen substituents on the benzene ring.
作为之前关于芳基二硫化物抗有丝分裂活性研究的延续,作者合成了3-和5-氯或氟取代的双-(2-氨基苯基)二硫化物及其一些2-N-烷基衍生物。合成这些化合物是为了对其进行生物测试,以发现苯环上卤素取代基所引起的任何活性。