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[免疫功能低下的恶性和非恶性血液疾病患者中巨细胞病毒感染(CMV)的发生率]

[The frequency of cytomegalovirus infection (CMV) in patients immunocompromised patients with malignant and nonmalignant blood disorders].

作者信息

Zawilińska B, Weglarska D, Gruszka A M, Skotnicki A B, Zgórniak-Nowosielska I

机构信息

Zakład Wirusologii Instytutu Mikrobiologii CMUJ.

出版信息

Acta Haematol Pol. 1996;27(1):65-71.

PMID:8629446
Abstract

Studies on CMV infection were carried out in a group of 110 patients, aged from 15 to 78 (average 38), treated in the Department of Haematology. During the course of observation most of the patients were examined repeatedly. Diagnosis was based on serology (CFT, ELISA) and virus isolation from the clinical material. Primary infection (seroconversion) was confirmed in 4 (21%) out of 19 seronegative patients. Seropositive patients comprised 83 per cent. Active CMV infection was determined in 20 (22%) of those patients.

摘要

对血液科收治的110例年龄在15至78岁(平均38岁)的患者进行了巨细胞病毒(CMV)感染研究。在观察过程中,大多数患者接受了多次检查。诊断基于血清学(补体结合试验、酶联免疫吸附测定)以及从临床材料中分离病毒。19例血清阴性患者中有4例(21%)确诊为原发性感染(血清转化)。血清阳性患者占83%。在这些患者中有20例(22%)被确定为活动性CMV感染。

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