Rapelanoro R, Mortureux P, Couprie B, Maleville J, Taïeb A
Pediatric Dermatology Unit, Pellegrin Children's Hospital, Bordeaux, France.
Arch Dermatol. 1996 Feb;132(2):190-3.
Papulopustular eruptions of the face in neonates are frequently referred to as neonatal acne or sebaceous miliaria. Our findings suggest that there is an association between this type of eruption and Malassezia furfur infection.
Direct examination of pustule smears showed M furfur yeasts in eight of 13 cases involving neonates with erythema and papulopustules of the face, neck, and scalp (mean age at onset, 22 days [range, 7 to 30 days]). The pustules were predominantly neutrophilic. Treatment with 2% ketoconazole cream applied topically twice daily was effective in 1 week.
Malassezia furfur is frequently associated with a common nonfollicular pustulosis of the newborn, probably improperly termed neonatal acne.
新生儿面部的丘疹脓疱性皮疹常被称为新生儿痤疮或粟丘疹。我们的研究结果表明，这类皮疹与糠秕马拉色菌感染之间存在关联。
对13例面部、颈部和头皮出现红斑及丘疹脓疱的新生儿（发病时平均年龄22天[范围7至30天]）的脓疱涂片进行直接检查，发现其中8例有糠秕马拉色菌酵母。脓疱主要为嗜中性粒细胞性。每日两次外用2%酮康唑乳膏治疗1周有效。
糠秕马拉色菌常与一种常见的新生儿非毛囊性脓疱病相关，该病可能被不恰当地称为新生儿痤疮。
