Hauswald M, Ong G, Hun Y B, Tan P S
Department of Emergency Medicine, University of New Mexico School of Medicine, Albuquerque 87131-5246, USA.
Am J Emerg Med. 1996 Jan;14(1):48-9. doi: 10.1016/S0735-6757(96)90014-5.
An animal study was conducted to determine whether an endotracheal tube placed above the vocal cords in the pharynx can be used for ventilation. Four dogs undergoing general anesthesia were ventilated through an endotracheal tube placed in the oropharynx with the remainder of the airway occluded. Ventilation was performed for 3 of every 5 minutes during a total period of 25 minutes. Arterial PCO2 was compared in sequential samples alternating apnea and pharyngeal ventilation. Ventilation via the pharyngeal tube significantly reduced the arterial PCO2 from 48.8 mm Hg (SD 16) during apnea to 30.1 mm Hg (SD 10.9). Repeated measures ANOVAF = 8.2, P < .001. All PCO2 levels during ventilation were in or below the normal range of 34 to 46. Provided that the mouth and nose can be sealed, an endotracheal tube placed in the pharynx above the cords allows for adequate ventilation.
进行了一项动物研究，以确定放置在咽部声带上方的气管内导管是否可用于通气。对四只接受全身麻醉的狗通过放置在口咽的气管内导管进行通气，同时阻塞气道的其余部分。在总共25分钟的时间内，每5分钟中有3分钟进行通气。在交替出现呼吸暂停和咽部通气的连续样本中比较动脉PCO2。通过咽部导管通气可使动脉PCO2从呼吸暂停时的48.8 mmHg（标准差16）显著降低至30.1 mmHg（标准差10.9）。重复测量方差分析F = 8.2，P <.001。通气期间所有PCO2水平均在34至46的正常范围内或以下。如果口鼻能够密封，放置在声带上方咽部的气管内导管可实现充分通气。
