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Quantitative analysis of carcinoembryonic antigen, squamous cell carcinoma antigen, CA 125, and CA 50 cytosolic content in non-small cell lung cancer.非小细胞肺癌中癌胚抗原、鳞状细胞癌抗原、CA 125和CA 50胞质含量的定量分析。
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Serum tumor markers CEA, CA 50, TATI, and NSE in lung cancer screening.血清肿瘤标志物癌胚抗原（CEA）、糖类抗原50（CA 50）、组织多肽特异性抗原（TATI）及神经元特异性烯醇化酶（NSE）在肺癌筛查中的应用
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Clinical usefulness of serum assays of neuron-specific enolase, carcinoembryonic antigen and CA-50 antigen in the diagnosis of lung cancer.血清神经元特异性烯醇化酶、癌胚抗原和CA-50抗原检测在肺癌诊断中的临床应用价值
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Quantitative analysis of carcinoembryonic antigen, squamous cell carcinoma antigen, CA 125, and CA 50 cytosolic content in non-small cell lung cancer.非小细胞肺癌中癌胚抗原、鳞状细胞癌抗原、CA 125和CA 50胞质含量的定量分析。
Cancer. 1994 May 1;73(9):2305-11. doi: 10.1002/1097-0142(19940501)73:9<2305::aid-cncr2820730911>3.0.co;2-d.
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血清和细胞溶质中癌胚抗原（CEA）、糖类抗原125（CA125）及鳞状细胞癌抗原（SCC）水平对可切除非小细胞肺癌生存及复发的预测作用

Prediction of survival and recurrence by serum and cytosolic levels of CEA, CA125 and SCC antigens in resectable non-small-cell lung cancer.

作者信息

Díez M, Torres A, Maestro M L, Ortega M D, Gómez A, Pollán M, Lopez J A, Picardo A, Hernando F, Balibrea J L

机构信息

San Carlos University Hospital, Madrid, Spain.

出版信息

Br J Cancer. 1996 May;73(10):1248-54. doi: 10.1038/bjc.1996.239.

DOI:10.1038/bjc.1996.239
PMID:8630287
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2074500/
Abstract

Risk of death and risk of recurrence in 108 potentially curable non-small-cell lung cancer patients were analysed with respect of TNM stage, histological type and carcinoembryonic antigen (CEA), CA125 antigen and squamous cell carcinoma antigen (SCC) levels in serum and cytosol. CA125 and CEA levels were closely related to outcome figures. Multivariate analyses indicated that TNM stage and histological type had the best predictive power, but serum and cytosolic CA125 and serum CEA contained additional, independent prognostic information. Predictive information drawn from serum and cytosolic levels proved mutually complementary. We conclude that CA125 and CEA complement TNM classification and histological type for the purpose of quantifying risk of death or recurrence.

摘要

对108例潜在可治愈的非小细胞肺癌患者的死亡风险和复发风险进行了分析，分析内容涉及TNM分期、组织学类型以及血清和细胞溶质中的癌胚抗原（CEA）、CA125抗原和鳞状细胞癌抗原（SCC）水平。CA125和CEA水平与预后数据密切相关。多变量分析表明，TNM分期和组织学类型具有最佳预测能力，但血清和细胞溶质中的CA125以及血清CEA包含额外的独立预后信息。从血清和细胞溶质水平得出的预测信息相互补充。我们得出结论，为了量化死亡或复发风险，CA125和CEA可补充TNM分类和组织学类型。