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[急性低温对温血动物心肌线粒体脂质成分的影响]

[Effect of acute hypothermia on the lipid composition of the myocardial mitochondria of warm-blooded animals].

作者信息

Shepelev A P

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1977 Mar;63(3):442-7.

PMID:863041
Abstract

In dogs and albino rats, artificial drop of body temperature by 8--10 degrees C elicits change of phospholipid spectre and increases amount of unsaturated fatty acids in lipids of the myocardium mitochondria. Drop of the temperature by 18--20 degrees C decreased amount of polyen fatty acids in dogs but caused no changes in the high amount of unsaturated lipids in rats. Role of of these facts in mitochondrial functions during hypothermia and possible dependence of the animals resistance against low temperature of the degree of membrane lipids reorganization, are discussed.

摘要

在狗和白化大鼠中,体温人工下降8 - 10摄氏度会引发心肌线粒体磷脂谱的变化,并增加脂质中不饱和脂肪酸的含量。体温下降18 - 20摄氏度会使狗体内多烯脂肪酸的含量减少,但对大鼠体内大量不饱和脂质没有影响。本文讨论了这些事实在低温期间线粒体功能中的作用,以及动物对低温的抵抗力可能与膜脂重组程度的依赖性。

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