[Clinico-biochemical comparisons in the acute period of craniocerebral trauma].

The content of prostaglandin F2 alpha was evaluated in the venous blood of 114 young male patients with acute craniocerebral injury of light to moderate severity. Prostaglandin content was determined by a gas/liquid chromatography technique. In the investigations carried out, the blood level of prostaglandin F2 alpha was found to show a strong tendency to increase from the moment of injury and up to day 3 to 5 following which day it began to slowly decline. There seems to be an association between the above process and severity of injury. Mathematic analysis has shown the blood level of prostaglandin to correlate primarily with disorders in the vegetative subdivision of the nervous system.