Taĭtslin V I, Shogam I I, Genes V S, Azar'iants M K, Zalogina I A, Sedykh L I
Zh Nevrol Psikhiatr Im S S Korsakova. 1994;94(6):13-6.
Long-term follow-up of the subjects who have suffered closed brain injury showed that in comparison to matched controls the injured young subjects demonstrated abnormalities in lipid metabolism and coagulation tending to atherosclerosis. The limits of the values by which the patients significantly differed from the controls as well as 7 specific for the patients signs of lipid metabolism and coagulation impairment have been determined. From 1 to 5 specific indications registered in 67 +/- 5% patients allowed the diagnosis in them of the injury sequelae. The mechanisms of the above atherosclerotic shifts may work through neuroregulatory derangements common for brain injury and atherosclerotic encephalopathy and enhancement of atherosclerosis course by the craniocerebral damage.
对闭合性脑损伤患者的长期随访表明，与匹配的对照组相比，受伤的年轻患者在脂质代谢和凝血方面表现出异常，有动脉粥样硬化倾向。已确定患者与对照组有显著差异的数值范围，以及7项患者特有的脂质代谢和凝血功能受损迹象。在67±5%的患者中出现的1至5项特定指征有助于诊断其损伤后遗症。上述动脉粥样硬化变化的机制可能通过脑损伤和动脉粥样硬化性脑病常见的神经调节紊乱起作用，并通过颅脑损伤加速动脉粥样硬化进程。
