Lysenko H I, Handzha I M, Matiukha L F, Volobuieva Z V
Lik Sprava. 1995 May-Jun(5-6):77-80.
An evaluation was done of effectiveness of diprospane (prolonged action glucocorticosteroid) in rheumatoid arthritis. There have been studied parameters characterizing the articular syndrome, laboratory values during the course of complex therapy that incorporated intraarthrous administration of diprospane and a course of laser irradiation of the joints against a background of intake of non-steroid antiinflammatory preparations and basis therapy with methotrexate. Topical therapy incorporated into the complex of therapeutic measures applied in patients with rheumatoid arthritis was found to be associated with most stable and pronounced effect, especially in the arthrous form of the malady. Combined use of intraarthrous administration of diprospane and a course of laser therapy permits achieving a favourable effect after a single administration of this drug preparation.
对二丙泼尼立定(长效糖皮质激素)治疗类风湿性关节炎的有效性进行了评估。研究了在联合治疗过程中表征关节综合征的参数、实验室值,联合治疗包括关节内注射二丙泼尼立定以及在服用非甾体抗炎制剂和甲氨蝶呤基础治疗的背景下对关节进行一个疗程的激光照射。在类风湿性关节炎患者所采用的综合治疗措施中加入局部治疗后发现其具有最稳定且显著的效果,尤其是在疾病的关节型中。关节内注射二丙泼尼立定与一个疗程的激光治疗联合使用,单次给药该药物制剂后即可取得良好效果。